The CD305 antibody (PE) from MyBioSource.com is a Hamster Monoclonal antibody. The CD305 antibody (PE) has been validated for the following applications: Flow Cytometry.
Description
Armenian Hamster monoclonal CD305 antibody (PE)
CD305 or Leukocyte-associated Ig-like receptor-1 is a 46 kD cell surface molecule that functions as an inhibitory collagen-receptor on the majority of cells of the immune system. The mouse LAIR-1 molecule is expressed primarily on monocytes/macrophages and also on T cells, NK cells and dendritic cells. Unlike human B cells, mouse B cells do not express LAIR-1. The cytoplasmic tail of mouse LAIR-1 can be phosphorylated leading to the recruitment of SH2-containing tyrosine phosphatase-2 and C-terminal Src kinase